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In this article, this pathway is placed in two broader contexts.

The first is that of nematodes and animals in general.

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Some species are characterized as sequential hermaphrodites, which means they hatch as one sex and then change sex later in life, depending on the population size and availability of mates.

Others are simultaneous hermaphrodites, which means the fish can fertilize its own egg with sperm.

This contrasts simultaneous hermaphrodites, in which an individual may possess fully functional male and female gonads.

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From all of these studies, a picture emerges in which biology to be systematically characterized with genetic analysis (Hodgkin and Brenner, 1977), and the depth of this analysis has made it a major topic in developmental biology.